CTLA4_HUMAN P16410
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UniProt:P16410
Recommended name:Cytotoxic T-lymphocyte protein 4
EC number:
Alternative names:(Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)
Cleaved into:
GeneID:1493
Gene names (primary ):CTLA4
Gene names (synonym ):CD152
Gene names (ORF ):
Length:223
Mass:24656
Sequence:MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
Tissue specificity:Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. {ECO:0000269|PubMed:10493833, ECO:0000269|PubMed:16551244, ECO:0000269|PubMed:1713603}.
Induction:
Developmental stage:
Protein families: