CTLA4_HUMAN   P16410


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UniProt:P16410

Recommended name:Cytotoxic T-lymphocyte protein 4

EC number:

Alternative names:(Cytotoxic T-lymphocyte-associated antigen 4) (CTLA-4) (CD antigen CD152)

Cleaved into:

GeneID:1493

Gene names  (primary ):CTLA4

Gene names  (synonym ):CD152

Gene names  (ORF ):

Length:223

Mass:24656

Sequence:MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN

Tissue specificity:Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation. {ECO:0000269|PubMed:10493833, ECO:0000269|PubMed:16551244, ECO:0000269|PubMed:1713603}.

Induction:

Developmental stage:

Protein families:


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