CRTAM_HUMAN O95727
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UniProt:O95727
Recommended name：Cytotoxic and regulatory T-cell molecule
EC number：
Alternative names：(Class-I MHC-restricted T-cell-associated molecule) (CD antigen CD355)
Cleaved into：
GeneID：56253
Gene names (primary )：CRTAM
Gene names (synonym )：
Gene names (ORF )：
Length：393
Mass：44641
Sequence：MWWRVLSLLAWFPLQEASLTNHTETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLSITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCSTMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKNSTVDCIIRHRGLQGRKLVAPFRFEDLVTDEETASDALERNSLSSQDPQQPTSTVSVTEDSSTSEIDKEEKEQTTQDPDLTTEANPQYLGLARKKSGILLLTLVSFLIFILFIIVQLFIMKLRKAHVIWKKENEVSEHTLESYRSRSNNEETSSEEKNGQSSHPMRCMNYITKLYSEAKTKRKENVQHSKLEEKHIQVPESIV
Tissue specificity：In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 T-cells (PubMed:10811014, PubMed:15811952, PubMed:16300832). Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues (PubMed:16300832). {ECO:0000269|PubMed:10811014, ECO:0000269|PubMed:15811952, ECO:0000269|PubMed:16300832}.
Induction：
Developmental stage：
Protein families：Nectin family