TMCO1_HUMAN Q9UM00
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UniProt:Q9UM00
Recommended name:Calcium load-activated calcium channel
EC number:
Alternative names:(CLAC channel) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3)
Cleaved into:
GeneID:54499
Gene names (primary ):TMCO1
Gene names (synonym ):TMCC4
Gene names (ORF ):PNAS-10 PNAS-136 UNQ151/PRO177
Length:239
Mass:27079
Sequence:MPRKRKCDLRAVRVGLLLGGGGVYGSRFRFTFPGCRALSPWRVRVQRRRCEMSTMFADTLLIVFISVCTALLAEGITWVLVYRTDKYKRLKAEVEKQSKKLEKKKETITESAGRQQKKKIERQEEKLKNNNRDLSMVRMKSMFAIGFCFTALMGMFNSIFDGRVVAKLPFTPLSYIQGLSHRNLLGDDTTDCSFIFLYILCTMSIRQNIQKILGLAPSRAATKQAGGFLGPPPPSGKFS
Tissue specificity:Widely expressed in adult and fetal tissues, with higher levels in thymus, prostate, testis and small intestine and lower levels in brain, placenta, lung and kidney (PubMed:10393320, PubMed:20018682). Present in most tissues in the eye, including the trabecular meshwork and retina (at protein level) (PubMed:22714896). {ECO:0000269|PubMed:10393320, ECO:0000269|PubMed:20018682, ECO:0000269|PubMed:22714896}.
Induction:
Developmental stage:
Protein families:TMCO1 family