CASP3_HUMAN P42574
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UniProt:P42574
Recommended name：Caspase-3
EC number：EC:3.4.22.56
Alternative names：(CASP-3) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1)
Cleaved into：Caspase-3 subunit p17; Caspase-3 subunit p12
GeneID：836
Gene names (primary )：CASP3
Gene names (synonym )：CPP32
Gene names (ORF )：
Length：277
Mass：31608
Sequence：MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
Tissue specificity：Highly expressed in lung, spleen, heart, liver and kidney. Moderate levels in brain and skeletal muscle, and low in testis. Also found in many cell lines, highest expression in cells of the immune system.
Induction：
Developmental stage：
Protein families：Peptidase C14A family