CLC4C_HUMAN Q8WTT0
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UniProt:Q8WTT0
Recommended name:C-type lectin domain family 4 member C
EC number:
Alternative names:(Blood dendritic cell antigen 2) (BDCA-2) (C-type lectin superfamily member 7) (Dendritic lectin) (CD antigen CD303)
Cleaved into:
GeneID:170482
Gene names (primary ):CLEC4C
Gene names (synonym ):BDCA2 CLECSF11 CLECSF7 DLEC HECL
Gene names (ORF ):UNQ9361/PRO34150
Length:213
Mass:25038
Sequence:MVPEEEPQDREKGLWWFQLKVWSMAVVSILLLSVCFTVSSVVPHNFMYSKTVKRLSKLREYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI
Tissue specificity:Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. {ECO:0000269|PubMed:11031109, ECO:0000269|PubMed:11536172, ECO:0000269|PubMed:11748283}.
Induction:
Developmental stage:
Protein families: