BDNF_HUMAN   P23560


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UniProt:P23560

Recommended name:Brain-derived neurotrophic factor

EC number:

Alternative names:(BDNF) (Abrineurin)

Cleaved into:BDNF precursor form (ProBDNF)

GeneID:627

Gene names  (primary ):BDNF

Gene names  (synonym ):

Gene names  (ORF ):

Length:247

Mass:27818

Sequence:MTILFLTMVISYFGCMKAAPMKEANIRGQGGLAYPGVRTHGTLESVNGPKAGSRGLTSLADTFEHVIEELLDEDQKVRPNEENNKDADLYTSRVMLSSQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR

Tissue specificity:Detected in blood plasma and in saliva (at protein level) (PubMed:11152678, PubMed:19467646). Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta. {ECO:0000269|PubMed:11152678, ECO:0000269|PubMed:17629449, ECO:0000269|PubMed:19467646, ECO:0000269|PubMed:2236018}.

Induction:

Developmental stage:

Protein families:NGF-beta family


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