ASIC2_HUMAN Q16515
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UniProt:Q16515
Recommended name:Acid-sensing ion channel 2
EC number:
Alternative names:(ASIC2) (Amiloride-sensitive brain sodium channel) (Amiloride-sensitive cation channel 1, neuronal) (Amiloride-sensitive cation channel neuronal 1) (Brain sodium channel 1) (BNC1) (BNaC1) (Mammalian degenerin homolog) (MDEG)
Cleaved into:
GeneID:40
Gene names (primary ):ASIC2
Gene names (synonym ):ACCN ACCN1 BNAC1 MDEG
Gene names (ORF ):
Length:512
Mass:57709
Sequence:MDLKESPSEGSLQPSSIQIFANTSTLHGIRHIFVYGPLTIRRVLWAVAFVGSLGLLLVESSERVSYYFSYQHVTKVDEVVAQSLVFPAVTLCNLNGFRFSRLTTNDLYHAGELLALLDVNLQIPDPHLADPSVLEALRQKANFKHYKPKQFSMLEFLHRVGHDLKDMMLYCKFKGQECGHQDFTTVFTKYGKCYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPPPWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAPFCTPEQHKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILTILELFDYIYELIKEKLLDLLGKEEDEGSHDENVSTCDTMPNHSETISHTVNVPLQTTLGTLEEIAC
Tissue specificity:Brain and spinal cord. Isoform 1 is also detected in testis, liver, colon and ovary. {ECO:0000269|PubMed:10842183, ECO:0000269|PubMed:8631835}.
Induction:
Developmental stage:
Protein families:Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC2 subfamily