GP15L_HUMAN Q6UWK7
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UniProt:Q6UWK7
Recommended name:Protein GPR15L
EC number:
Alternative names:(Antimicrobial peptide with 57 amino acid residues) (AP-57) (Antimicrobial peptide-57) (Colon-derived SUSD2 binding factor) (CSBF) (Secreted protein C10orf99)
Cleaved into:
GeneID:387695
Gene names (primary ):GPR15L
Gene names (synonym ):C10orf99
Gene names (ORF ):UNQ1833/PRO3446
Length:81
Mass:9173
Sequence:MRLLVLSSLLCILLLCFSIFSTEGKRRPAKAWSGRRTRLCCHRVPSPNSTNLKGHHVRLCKPCKLEPEPRLWVVPGALPQV
Tissue specificity:Expressed at high levels in colon, and cervix and at moderate level in tonsil (PubMed:25585381, PubMed:28900043). Highly reduced expression in primary colon cancer tissues compared with that in adjacent tissues (PubMed:25351403). Highest levels of expression detected in stomach and colon; expressed in epithelium of skin and esophagus, and in some tumor and/or tumor adjacent tissues (TAT), including TAT of esophagus cancer, hepatocellular carcinoma (HCC), squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and invasive ductal carcinoma (IDC) tissues (at protein level) (PubMed:25585381). {ECO:0000269|PubMed:25585381, ECO:0000269|PubMed:28900043}.
Induction:
Developmental stage:
Protein families: