TPM1_HUMAN P09493
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UniProt:P09493
Recommended name:Tropomyosin alpha-1 chain
EC number:
Alternative names:(Alpha-tropomyosin) (Tropomyosin-1)
Cleaved into:
GeneID:7168
Gene names (primary ):TPM1
Gene names (synonym ):C15orf13 TMSA
Gene names (ORF ):
Length:284
Mass:32709
Sequence:MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Tissue specificity:Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle. {ECO:0000269|PubMed:15249230, ECO:0000269|Ref.15}.
Induction:
Developmental stage:
Protein families:Tropomyosin family