TPM1_HUMAN   P09493


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UniProt:P09493

Recommended name:Tropomyosin alpha-1 chain

EC number:

Alternative names:(Alpha-tropomyosin) (Tropomyosin-1)

Cleaved into:

GeneID:7168

Gene names  (primary ):TPM1

Gene names  (synonym ):C15orf13 TMSA

Gene names  (ORF ):

Length:284

Mass:32709

Sequence:MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI

Tissue specificity:Detected in primary breast cancer tissues but undetectable in normal breast tissues in Sudanese patients. Isoform 1 is expressed in adult and fetal skeletal muscle and cardiac tissues, with higher expression levels in the cardiac tissues. Isoform 10 is expressed in adult and fetal cardiac tissues, but not in skeletal muscle. {ECO:0000269|PubMed:15249230, ECO:0000269|Ref.15}.

Induction:

Developmental stage:

Protein families:Tropomyosin family


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