LICH_HUMAN P38571
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UniProt:P38571
Recommended name:Lysosomal acid lipase/cholesteryl ester hydrolase
EC number:EC:3.1.1.13
Alternative names:(Acid cholesteryl ester hydrolase) (LAL) (Cholesteryl esterase) (Lipase A) (Sterol esterase)
Cleaved into:
GeneID:3988
Gene names (primary ):LIPA
Gene names (synonym ):
Gene names (ORF ):
Length:399
Mass:45419
Sequence:MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ
Tissue specificity:Most abundantly expressed in brain, lung, kidney and mammary gland, a moderate expression seen in placenta and expressed at low levels in the liver and heart. {ECO:0000269|PubMed:8112342}.
Induction:
Developmental stage:
Protein families:AB hydrolase superfamily, Lipase family