PAG15_HUMAN   Q8NCC3


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UniProt:Q8NCC3

Recommended name:Lysosomal phospholipase A and acyltransferase

EC number:EC:2.3.1.- /3.1.1.32/3.1.1.4

Alternative names:(1-O-acylceramide synthase) (ACS) (LCAT-like lysophospholipase) (LLPL) (Lysophospholipase 3) (Lysosomal phospholipase A2) (LPLA2) (Phospholipase A2 group XV(PLA2G15 )

Cleaved into:

GeneID:23659

Gene names  (primary ):PLA2G15

Gene names  (synonym ):LYPLA3

Gene names  (ORF ):UNQ341/PRO540

Length:412

Mass:46658

Sequence:MGLHLRPYRVGLLPDGLLFLLLLLMLLADPALPAGRHPPVVLVPGDLGNQLEAKLDKPTVVHYLCSKKTESYFTIWLNLELLLPVIIDCWIDNIRLVYNKTSRATQFPDGVDVRVPGFGKTFSLEFLDPSKSSVGSYFHTMVESLVGWGYTRGEDVRGAPYDWRRAPNENGPYFLALREMIEEMYQLYGGPVVLVAHSMGNMYTLYFLQRQPQAWKDKYIRAFVSLGAPWGGVAKTLRVLASGDNNRIPVIGPLKIREQQRSAVSTSWLLPYNYTWSPEKVFVQTPTINYTLRDYRKFFQDIGFEDGWLMRQDTEGLVEATMPPGVQLHCLYGTGVPTPDSFYYESFPDRDPKICFGDGDGTVNLKSALQCQAWQSRQEHQVLLQELPGSEHIEMLANATTLAYLKRVLLGP

Tissue specificity:Detected in blood plasma (at protein level) (PubMed:10092508, PubMed:20410020). Ubiquitous. Highly expressed in heart, placenta, skeletal muscle, kidney and pancreas. Detected at lower levels in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes (PubMed:10092508). {ECO:0000269|PubMed:10092508, ECO:0000269|PubMed:20410020}.

Induction:

Developmental stage:

Protein families:AB hydrolase superfamily, Lipase family


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