DHB7_HUMAN   P56937


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UniProt:P56937

Recommended name:3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7

EC number:

Alternative names:(17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (3-keto-steroid reductase) (EC 1.1.1.270) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 37C member 1)

Cleaved into:

GeneID:51478

Gene names  (primary ):HSD17B7

Gene names  (synonym ):17HSD7 SDR37C1

Gene names  (ORF ):UNQ2563/PRO6243

Length:341

Mass:38206

Sequence:MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIWTLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQKMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL

Tissue specificity:Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested. {ECO:0000269|PubMed:12732193}.; [Isoform 3]: Expressed in eye ciliary epithelial cells and neuroendocrine cells. {ECO:0000269|PubMed:12732193}.

Induction:

Developmental stage:

Protein families:Short-chain dehydrogenases/reductases (SDR) family, ERG27 subfamily


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