RN182_HUMAN Q8N6D2
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UniProt:Q8N6D2
Recommended name:E3 ubiquitin-protein ligase RNF182
EC number:EC:2.3.2.27
Alternative names:(RING finger protein 182) (RING-type E3 ubiquitin transferase RNF182)
Cleaved into:
GeneID:221687
Gene names (primary ):RNF182
Gene names (synonym ):
Gene names (ORF ):
Length:247
Mass:27402
Sequence:MASQPPEDTAESQASDELECKICYNRYNLKQRKPKVLECCHRVCAKCLYKIIDFGDSPQGVIVCPFCRFETCLPDDEVSSLPDDNNILVNLTCGGKGKKCLPENPTELLLTPKRLASLVSPSHTSSNCLVITIMEVQRESSPSLSSTPVVEFYRPASFDSVTTVSHNWTVWNCTSLLFQTSIRVLVWLLGLLYFSSLPLGIYLLVSKKVTLGVVFVSLVPSSLVILMVYGFCQCVCHEFLDCMAPPS
Tissue specificity:Up-regulated in neuronal cells subjected to cell death-inducing injuries, such as oxygen and glucose deprivation (at protein level). Could be up-regulated in Alzheimer disease brains (PubMed:18298843). Highly expressed in innate immune organs such as lymph nodes and spleen and in immune cells such as macrophages and dendritic cells (PubMed:31432514). {ECO:0000269|PubMed:18298843, ECO:0000269|PubMed:31432514}.
Induction:
Developmental stage:
Protein families: