MCES_HUMAN O43148
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UniProt:O43148
Recommended name:mRNA cap guanine-N7 methyltransferase
EC number:EC:2.1.1.56
Alternative names:(RG7MT1) (mRNA(guanine-N(7)-)-methyltransferase) (mRNA cap methyltransferase) (hCMT1) (hMet) (hcm1p)
Cleaved into:
GeneID:8731
Gene names (primary ):RNMT
Gene names (synonym ):KIAA0398
Gene names (ORF ):
Length:476
Mass:54844
Sequence:MANSAKAEEYEKMSLEQAKASVNSETESSFNINENTTASGTGLSEKTSVCRQVDIARKRKEFEDDLVKESSSCGKDTPSKKRKLDPEIVPEEKDCGDAEGNSKKRKRETEDVPKDKSSTGDGTQNKRKIALEDVPEKQKNLEEGHSSTVAAHYNELQEVGLEKRSQSRIFYLRNFNNWMKSVLIGEFLEKVRQKKKRDITVLDLGCGKGGDLLKWKKGRINKLVCTDIADVSVKQCQQRYEDMKNRRDSEYIFSAEFITADSSKELLIDKFRDPQMCFDICSCQFVCHYSFESYEQADMMLRNACERLSPGGYFIGTTPNSFELIRRLEASETESFGNEIYTVKFQKKGDYPLFGCKYDFNLEGVVDVPEFLVYFPLLNEMAKKYNMKLVYKKTFLEFYEEKIKNNENKMLLKRMQALEPYPANESSKLVSEKVDDYEHAAKYMKNSQVRLPLGTLSKSEWEATSIYLVFAFEKQQ
Tissue specificity:Widely expressed. {ECO:0000269|PubMed:9705270, ECO:0000269|PubMed:9790902}.
Induction:
Developmental stage:
Protein families:Class I-like SAM-binding methyltransferase superfamily, mRNA cap 0 methyltransferase family