KCAB1_HUMAN Q14722
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UniProt:Q14722
Recommended name:Voltage-gated potassium channel subunit beta-1
EC number:EC:1.1.1.-
Alternative names:(K(+) channel subunit beta-1) (Kv-beta-1)
Cleaved into:
GeneID:7881
Gene names (primary ):KCNAB1
Gene names (synonym ):KCNA1B
Gene names (ORF ):
Length:419
Mass:46563
Sequence:MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
Tissue specificity:In brain, expression is most prominent in caudate nucleus, hippocampus and thalamus. Significant expression also detected in amygdala and subthalamic nucleus. Also expressed in both healthy and cardiomyopathic heart. Up to four times more abundant in left ventricle than left atrium. {ECO:0000269|PubMed:7603988, ECO:0000269|PubMed:8938711}.
Induction:
Developmental stage:
Protein families:Shaker potassium channel beta subunit family