ICMT_HUMAN O60725
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UniProt:O60725
Recommended name：Protein-S-isoprenylcysteine O-methyltransferase
EC number：EC:2.1.1.100
Alternative names：(Isoprenylcysteine carboxylmethyltransferase) (Prenylated protein carboxyl methyltransferase) (PPMT) (Prenylcysteine carboxyl methyltransferase) (pcCMT)
Cleaved into：
GeneID：23463
Gene names (primary )：ICMT
Gene names (synonym )：PCCMT
Gene names (ORF )：
Length：284
Mass：31938
Sequence：MAGCAARAPPGSEARLSLATFLLGASVLALPLLTRAGLQGRTGLALYVAGLNALLLLLYRPPRYQIAIRACFLGFVFGCGTLLSFSQSSWSHFGWYMCSLSLFHYSEYLVTAVNNPKSLSLDSFLLNHSLEYTVAALSSWLEFTLENIFWPELKQITWLSVTGLLMVVFGECLRKAAMFTAGSNFNHVVQNEKSDTHTLVTSGVYAWFRHPSYVGWFYWSIGTQVMLCNPICGVSYALTVWRFFRDRTEEEEISLIHFFGEEYLEYKKRVPTGLPFIKGVKVDL
Tissue specificity：Ubiquitously expressed. Expressed at higher levels in the cerebellum and putamen than in other brain regions. Abundant expression seen in the Purkinje cells and pontine neurons. {ECO:0000269|PubMed:10649571}.
Induction：
Developmental stage：
Protein families：Class VI-like SAM-binding methyltransferase superfamily, Isoprenylcysteine carboxyl methyltransferase family