PTGIS_HUMAN Q16647
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UniProt:Q16647
Recommended name：Prostacyclin synthase
EC number：EC:5.3.99.4
Alternative names：(Hydroperoxy icosatetraenoate dehydratase) (Prostaglandin I2 synthase)
Cleaved into：
GeneID：5740
Gene names (primary )：PTGIS
Gene names (synonym )：CYP8 CYP8A1
Gene names (ORF )：
Length：500
Mass：57104
Sequence：MAWAALLGLLAALLLLLLLSRRRTRRPGEPPLDLGSIPWLGYALDFGKDAASFLTRMKEKHGDIFTILVGGRYVTVLLDPHSYDAVVWEPRTRLDFHAYAIFLMERIFDVQLPHYSPSDEKARMKLTLLHRELQALTEAMYTNLHAVLLGDATEAGSGWHEMGLLDFSYSFLLRAGYLTLYGIEALPRTHESQAQDRVHSADVFHTFRQLDRLLPKLARGSLSVGDKDHMCSVKSRLWKLLSPARLARRAHRSKWLESYLLHLEEMGVSEEMQARALVLQLWATQGNMGPAAFWLLLFLLKNPEALAAVRGELESILWQAEQPVSQTTTLPQKVLDSTPVLDSVLSESLRLTAAPFITREVVVDLAMPMADGREFNLRRGDRLLLFPFLSPQRDPEIYTDPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNHCLGRSYAVNSIKQFVFLVLVHLDLELINADVEIPEFDLSRYGFGLMQPEHDVPVRYRIRP
Tissue specificity：Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate. {ECO:0000269|PubMed:8185632}.
Induction：
Developmental stage：
Protein families：Cytochrome P450 family