ANM1_HUMAN   Q99873


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UniProt:Q99873

Recommended name:Protein arginine N-methyltransferase 1

EC number:EC:2.1.1.319

Alternative names:(Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4)

Cleaved into:

GeneID:3276

Gene names  (primary ):PRMT1

Gene names  (synonym ):HMT2 HRMT1L2 IR1B4

Gene names  (ORF ):

Length:371

Mass:42462

Sequence:MAAAEAANCIMENFVATLANGMSLQPPLEEVSCGQAESSEKPNAEDMTSKDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEFTRCHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLDFKGQLCELSCSTDYRMR

Tissue specificity:Widely expressed (PubMed:11097842). Expressed strongly in colorectal cancer cells (at protein level) (PubMed:28040436). Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (at protein level) (PubMed:28040436). Expressed strongly in colorectal cancer tissues compared to wild-type colon samples (PubMed:28040436). {ECO:0000269|PubMed:11097842, ECO:0000269|PubMed:28040436}.

Induction:

Developmental stage:

Protein families:Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family


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