GGT1_HUMAN   P19440


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UniProt:P19440

Recommended name:Glutathione hydrolase 1 proenzyme

EC number:EC:3.4.19.13

Alternative names:(Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (Leukotriene-C4 hydrolase) (CD antigen CD224)

Cleaved into:Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain

GeneID:2678

Gene names  (primary ):GGT1

Gene names  (synonym ):GGT

Gene names  (ORF ):

Length:569

Mass:61410

Sequence:MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY

Tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific. {ECO:0000269|PubMed:7689219}.

Induction:

Developmental stage:

Protein families:Gamma-glutamyltransferase family


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