GGT1_HUMAN P19440
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UniProt:P19440
Recommended name:Glutathione hydrolase 1 proenzyme
EC number:EC:3.4.19.13
Alternative names:(Gamma-glutamyltransferase 1) (Gamma-glutamyltranspeptidase 1) (GGT 1) (Leukotriene-C4 hydrolase) (CD antigen CD224)
Cleaved into:Glutathione hydrolase 1 heavy chain; Glutathione hydrolase 1 light chain
GeneID:2678
Gene names (primary ):GGT1
Gene names (synonym ):GGT
Gene names (ORF ):
Length:569
Mass:61410
Sequence:MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFNSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY
Tissue specificity:Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein.; [Isoform 3]: Lung-specific. {ECO:0000269|PubMed:7689219}.
Induction:
Developmental stage:
Protein families:Gamma-glutamyltransferase family