GRK4_HUMAN P32298
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UniProt:P32298
Recommended name:G protein-coupled receptor kinase 4
EC number:EC:2.7.11.16
Alternative names:(G protein-coupled receptor kinase GRK4) (ITI1)
Cleaved into:
GeneID:2868
Gene names (primary ):GRK4
Gene names (synonym ):GPRK2L GPRK4
Gene names (ORF ):
Length:578
Mass:66583
Sequence:MELENIVANSLLLKARQGGYGKKSGRSKKWKEILTLPPVSQCSELRHSIEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKLAAPLPEIPPDVVTECRLGLKEENPSKKAFEECTRVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYACKKLQKKRIKKRKGEAMALNEKRILEKVQSRFVVSLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLKPENILLDDRGHIRISDLGLATEIPEGQRVRGRVGTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSEDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPVFKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIEQFSVVKGIYLDTADEDFYARFATGCVSIPWQNEMIESGCFKDINKSESEEALPLDLDKNIHTPVSRPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC
Tissue specificity:Isoform 1, isoform 2, isoform 3, and isoform 4 are expressed in testis. Isoform 4 is expressed in myometrium. {ECO:0000269|PubMed:16636192, ECO:0000269|PubMed:8626439}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, GPRK subfamily