WWOX_HUMAN Q9NZC7
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UniProt:Q9NZC7
Recommended name:WW domain-containing oxidoreductase
EC number:EC:1.1.1.-
Alternative names:(Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Cleaved into:
GeneID:51741
Gene names (primary ):WWOX
Gene names (synonym ):FOR SDR41C1 WOX1
Gene names (ORF ):
Length:414
Mass:46677
Sequence:MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRLAFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLIQERLGSQSG
Tissue specificity:Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines. {ECO:0000269|PubMed:10786676, ECO:0000269|PubMed:11719429}.
Induction:
Developmental stage:
Protein families:Short-chain dehydrogenases/reductases (SDR) family