MBTP2_HUMAN O43462
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UniProt:O43462
Recommended name:Membrane-bound transcription factor site-2 protease
EC number:EC:3.4.24.85
Alternative names:(Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease)
Cleaved into:
GeneID:51360
Gene names (primary ):MBTPS2
Gene names (synonym ):S2P
Gene names (ORF ):
Length:519
Mass:57444
Sequence:MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR
Tissue specificity:Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. {ECO:0000269|PubMed:9659902}.
Induction:
Developmental stage:
Protein families:Peptidase M50A family