MBTP2_HUMAN   O43462


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UniProt:O43462

Recommended name:Membrane-bound transcription factor site-2 protease

EC number:EC:3.4.24.85

Alternative names:(Endopeptidase S2P) (Sterol regulatory element-binding proteins intramembrane protease) (SREBPs intramembrane protease)

Cleaved into:

GeneID:51360

Gene names  (primary ):MBTPS2

Gene names  (synonym ):S2P

Gene names  (ORF ):

Length:519

Mass:57444

Sequence:MIPVSLVVVVVGGWTVVYLTDLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTAVFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSSYSSSSSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFTAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRTNKDCKKSSSSSFCIIPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVVVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR

Tissue specificity:Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. {ECO:0000269|PubMed:9659902}.

Induction:

Developmental stage:

Protein families:Peptidase M50A family


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