TRDMT_HUMAN   O14717


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UniProt:O14717

Recommended name:tRNA (cytosine(38)-C(5))-methyltransferase

EC number:EC:2.1.1.204

Alternative names:(DNA(cytosine-5)-methyltransferase-like protein 2) (Dnmt2) (DNA methyltransferase homolog HsaIIP) (DNA MTase homolog HsaIIP) (M.HsaIIP) (PuMet)

Cleaved into:

GeneID:1787

Gene names  (primary ):TRDMT1

Gene names  (synonym ):DNMT2

Gene names  (ORF ):

Length:391

Mass:44597

Sequence:MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLHILDILPRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAKLIKILYE

Tissue specificity:Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes.

Induction:

Developmental stage:

Protein families:Class I-like SAM-binding methyltransferase superfamily, C5-methyltransferase family


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