TOPK_HUMAN   Q96KB5


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UniProt:Q96KB5

Recommended name:Lymphokine-activated killer T-cell-originated protein kinase

EC number:EC:2.7.12.2

Alternative names:(Cancer/testis antigen 84) (CT84) (MAPKK-like protein kinase) (Nori-3) (PDZ-binding kinase) (Spermatogenesis-related protein kinase) (SPK) (T-LAK cell-originated protein kinase)

Cleaved into:

GeneID:55872

Gene names  (primary ):PBK

Gene names  (synonym ):TOPK

Gene names  (ORF ):

Length:322

Mass:36085

Sequence:MEGISNFKTPSKLSEKKKSVLCSTPTINIPASPFMQKLGFGTGVNVYLMKRSPRGLSHSPWAVKKINPICNDHYRSVYQKRLMDEAKILKSLHHPNIVGYRAFTEANDGSLCLAMEYGGEKSLNDLIEERYKASQDPFPAAIILKVALNMARGLKYLHQEKKLLHGDIKSSNVVIKGDFETIKICDVGVSLPLDENMTVTDPEACYIGTEPWKPKEAVEENGVITDKADIFAFGLTLWEMMTLSIPHINLSNDDDDEDKTFDESDFDDEAYYAALGTRPPINMEELDESYQKVIELFSVCTNEDPKDRPSAAHIVEALETDV

Tissue specificity:Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules. {ECO:0000269|PubMed:10781613, ECO:0000269|PubMed:11378444}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase subfamily


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