BRCC3_HUMAN P46736
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UniProt:P46736
Recommended name:Lys-63-specific deubiquitinase BRCC36
EC number:EC:3.4.19.-
Alternative names:(BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Cleaved into:
GeneID:79184
Gene names (primary ):BRCC3
Gene names (synonym ):BRCC36 C6.1A CXorf53
Gene names (ORF ):
Length:316
Mass:36072
Sequence:MAVQVVQAVQAVHLESDAFLVCLNHALSTEKEEVMGLCIGELNDDTRSDSKFAYTGTEMRTVAEKVDAVRIVHIHSVIILRRSDKRKDRVEISPEQLSAASTEAERLAELTGRPMRVVGWYHSHPHITVWPSHVDVRTQAMYQMMDQGFVGLIFSCFIEDKNTKTGRVLYTCFQSIQAQKSSESLHGPRDFWSSSQHISIEGQKEEERYERIEIPIHIVPHVTIGKVCLESAVELPKILCQEEQDAYRRIHSLTHLDSVTKIHNGSVFTKNLCSQMSAVSGPLLQWLEDRLEQNQQHLQELQQEKEELMQELSSLE
Tissue specificity:Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Aberrantly expressed in the vast majority of breast tumors. {ECO:0000269|PubMed:16707425}.
Induction:
Developmental stage:
Protein families:Peptidase M67A family, BRCC36 subfamily