SAST_HUMAN   Q9NV23


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UniProt:Q9NV23

Recommended name:S-acyl fatty acid synthase thioesterase, medium chain

EC number:EC:3.1.2.14

Alternative names:(Augmented in rheumatoid arthritis 1) (AURA1) (Oleoyl-ACP hydrolase) (Thioesterase 2) (TE2) (Thioesterase II) (Thioesterase domain-containing protein 1)

Cleaved into:

GeneID:55301

Gene names  (primary ):OLAH

Gene names  (synonym ):THEDC1

Gene names  (ORF ):

Length:265

Mass:29931

Sequence:MERGDQPKRTRNENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLRLPGRESRVEEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF

Tissue specificity:Detected both in lactating and non-lactating breast epithelium (at protein level) (PubMed:6589427). Isoform 2 is up-regulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients (PubMed:17082220). {ECO:0000269|PubMed:17082220, ECO:0000269|PubMed:6589427}.

Induction:

Developmental stage:

Protein families:Thioesterase family


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