SAST_HUMAN Q9NV23
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UniProt:Q9NV23
Recommended name:S-acyl fatty acid synthase thioesterase, medium chain
EC number:EC:3.1.2.14
Alternative names:(Augmented in rheumatoid arthritis 1) (AURA1) (Oleoyl-ACP hydrolase) (Thioesterase 2) (TE2) (Thioesterase II) (Thioesterase domain-containing protein 1)
Cleaved into:
GeneID:55301
Gene names (primary ):OLAH
Gene names (synonym ):THEDC1
Gene names (ORF ):
Length:265
Mass:29931
Sequence:MERGDQPKRTRNENIFNCLYKNPEATFKLICFPWMGGGSTHFAKWGQDTHDLLEVHSLRLPGRESRVEEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALGLKENNQPEPLHLFLSSATPVHSKAWHRIPKDDELSEEQISHYLMEFGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAKDMEAWKDVTSGNAKIYQLPGGHFYLLDPANEKLIKNYIIKCLEVSSISNF
Tissue specificity:Detected both in lactating and non-lactating breast epithelium (at protein level) (PubMed:6589427). Isoform 2 is up-regulated in bone marrow-derived mononuclear cells of rheumatoid arthritis patients (PubMed:17082220). {ECO:0000269|PubMed:17082220, ECO:0000269|PubMed:6589427}.
Induction:
Developmental stage:
Protein families:Thioesterase family