CATB_HUMAN P07858
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UniProt:P07858
Recommended name：Cathepsin B
EC number：EC:3.4.22.1
Alternative names：(APP secretase) (APPS) (Cathepsin B1)
Cleaved into：Cathepsin B light chain; Cathepsin B heavy chain
GeneID：1508
Gene names (primary )：CTSB
Gene names (synonym )：CPSB
Gene names (ORF )：
Length：339
Mass：37822
Sequence：MWQLWASLCCLLVLANARSRPSFHPLSDELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVTGEMMGGHAIRILGWGVENGTPYWLVANSWNTDWGDNGFFKILRGQDHCGIESEVVAGIPRTDQYWEKI
Tissue specificity：Expressed in the stratum spinosum of the epidermis. Weak expression is detected in the stratum granulosum. {ECO:0000269|PubMed:28457472}.
Induction：
Developmental stage：
Protein families：Peptidase C1 family