TM11A_HUMAN Q6ZMR5
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UniProt:Q6ZMR5
Recommended name:Transmembrane protease serine 11A
EC number:EC:3.4.21.-
Alternative names:(Airway trypsin-like protease 1) (Epidermal type-II transmembrane serine protease) (Esophageal cancer-susceptibility gene 1 protein)
Cleaved into:
GeneID:339967
Gene names (primary ):TMPRSS11A
Gene names (synonym ):ECRG1 HATL1 HESP
Gene names (ORF ):
Length:421
Mass:47569
Sequence:MMYRTVGFGTRSRNLKPWMIAVLIVLSLTVVAVTIGLLVHFLVFDQKKEYYHGSFKILDPQINNNFGQSNTYQLKDLRETTENLVSQVDEIFIDSAWKKNYIKNQVVRLTPEEDGVKVDVIMVFQFPSTEQRAVREKKIQSILNQKIRNLRALPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQASLQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQWTVSFGTKINPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRRICLPEASASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWIASKTGI
Tissue specificity:Expressed in esophagus, liver, colon and lung. Down-regulated in esophagus cancers. {ECO:0000269|PubMed:10920976}.
Induction:
Developmental stage:
Protein families:Peptidase S1 family