ACV1C_HUMAN Q8NER5
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UniProt:Q8NER5
Recommended name:Activin receptor type-1C
EC number:EC:2.7.11.30
Alternative names:(Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7)
Cleaved into:
GeneID:130399
Gene names (primary ):ACVR1C
Gene names (synonym ):ALK7
Gene names (ORF ):
Length:493
Mass:54871
Sequence:MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA
Tissue specificity:Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy. {ECO:0000269|PubMed:12063393, ECO:0000269|PubMed:12606401}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily