ACV1C_HUMAN   Q8NER5


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UniProt:Q8NER5

Recommended name:Activin receptor type-1C

EC number:EC:2.7.11.30

Alternative names:(Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7)

Cleaved into:

GeneID:130399

Gene names  (primary ):ACVR1C

Gene names  (synonym ):ALK7

Gene names  (ORF ):

Length:493

Mass:54871

Sequence:MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA

Tissue specificity:Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy. {ECO:0000269|PubMed:12063393, ECO:0000269|PubMed:12606401}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily


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