IOD2_HUMAN Q92813
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UniProt:Q92813
Recommended name:Type II iodothyronine deiodinase
EC number:EC:1.21.99.4
Alternative names:(5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase)
Cleaved into:
GeneID:1734
Gene names (primary ):DIO2
Gene names (synonym ):ITDI2 TXDI2
Gene names (ORF ):
Length:273
Mass:30552
Sequence:MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG
Tissue specificity:Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:8755651, PubMed:11165050). Isoform 2 is expressed in the brain, heart, kidney and trachea (PubMed:11165050). {ECO:0000269|PubMed:11165050, ECO:0000269|PubMed:8755651}.
Induction:
Developmental stage:
Protein families:Iodothyronine deiodinase family