IOD2_HUMAN   Q92813


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UniProt:Q92813

Recommended name:Type II iodothyronine deiodinase

EC number:EC:1.21.99.4

Alternative names:(5DII) (DIOII) (Type 2 DI) (Type-II 5'-deiodinase)

Cleaved into:

GeneID:1734

Gene names  (primary ):DIO2

Gene names  (synonym ):ITDI2 TXDI2

Gene names  (ORF ):

Length:273

Mass:30552

Sequence:MGILSVDLLITLQILPVFFSNCLFLALYDSVILLKHVVLLLSRSKSTRGEWRRMLTSEGLRCVWKSFLLDAYKQVKLGEDAPNSSVVHVSSTEGGDNSGNGTQEKIAEGATCHLLDFASPERPLVVNFGSATUPPFTSQLPAFRKLVEEFSSVADFLLVYIDEAHPSDGWAIPGDSSLSFEVKKHQNQEDRCAAAQQLLERFSLPPQCRVVADRMDNNANIAYGVAFERVCIVQRQKIAYLGGKGPFSYNLQEVRHWLEKNFSKRUKKTRLAG

Tissue specificity:Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:8755651, PubMed:11165050). Isoform 2 is expressed in the brain, heart, kidney and trachea (PubMed:11165050). {ECO:0000269|PubMed:11165050, ECO:0000269|PubMed:8755651}.

Induction:

Developmental stage:

Protein families:Iodothyronine deiodinase family


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