DHB12_HUMAN Q53GQ0
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UniProt:Q53GQ0
Recommended name：Very-long-chain 3-oxoacyl-CoA reductase
EC number：EC:1.1.1.330
Alternative names：(17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (Short chain dehydrogenase/reductase family 12C member 1)
Cleaved into：
GeneID：51144
Gene names (primary )：HSD17B12
Gene names (synonym )：SDR12C1
Gene names (ORF )：
Length：312
Mass：34324
Sequence：MESALPAAGFLYWVGAGTVAYLALRISYSLFTALRVWGVGNEAGVGPGLGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASEDIYDKIKTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGLQSRTNGYLIHALMGSIISNLPSWIYLKIVMNMNKSTRAHYLKKTKKN
Tissue specificity：Expressed in most tissues tested. Highly expressed in the ovary and mammary. Expressed in platelets. {ECO:0000269|PubMed:12482854, ECO:0000269|PubMed:16113833, ECO:0000269|PubMed:16166196}.
Induction：
Developmental stage：
Protein families：Short-chain dehydrogenases/reductases (SDR) family, 17-beta-HSD 3 subfamily