DHI1_HUMAN   P28845


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UniProt:P28845

Recommended name:Corticosteroid 11-beta-dehydrogenase isozyme 1

EC number:EC:1.1.1.146

Alternative names:(11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)

Cleaved into:

GeneID:3290

Gene names  (primary ):HSD11B1

Gene names  (synonym ):HSD11 HSD11L SDR26C1

Gene names  (ORF ):

Length:292

Mass:32401

Sequence:MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK

Tissue specificity:Widely expressed. Highest expression in liver.

Induction:

Developmental stage:

Protein families:Short-chain dehydrogenases/reductases (SDR) family


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