DHI1_HUMAN P28845
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UniProt:P28845
Recommended name:Corticosteroid 11-beta-dehydrogenase isozyme 1
EC number:EC:1.1.1.146
Alternative names:(11-beta-hydroxysteroid dehydrogenase 1) (11-DH) (11-beta-HSD1) (Short chain dehydrogenase/reductase family 26C member 1)
Cleaved into:
GeneID:3290
Gene names (primary ):HSD11B1
Gene names (synonym ):HSD11 HSD11L SDR26C1
Gene names (ORF ):
Length:292
Mass:32401
Sequence:MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK
Tissue specificity:Widely expressed. Highest expression in liver.
Induction:
Developmental stage:
Protein families:Short-chain dehydrogenases/reductases (SDR) family