PLS1_HUMAN O15162
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UniProt:O15162
Recommended name：Phospholipid scramblase 1
EC number：EC:3.1.-.-
Alternative names：(PL scramblase 1) (Ca(2+)-dependent phospholipid scramblase 1) (Erythrocyte phospholipid scramblase) (Mg(2+)-dependent nuclease) (MmTRA1b)
Cleaved into：
GeneID：5359
Gene names (primary )：PLSCR1
Gene names (synonym )：
Gene names (ORF )：
Length：318
Mass：35049
Sequence：MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPPAGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLEYLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCTRNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPGVPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSLDEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLIDFMFFESTGSQEQKSGVW
Tissue specificity：Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle. {ECO:0000269|PubMed:10930526, ECO:0000269|PubMed:9218461}.
Induction：(Microbial infection) Induced by IFNB1/IFN-beta in response to a viral infection. {ECO:0000269|PubMed:15308695}.; Up-regulated during PMA-induced differentiation of the monocytic cell line THP-1. {ECO:0000269|PubMed:26745724}.
Developmental stage：
Protein families：Phospholipid scramblase family