DYRK2_HUMAN Q92630
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UniProt:Q92630
Recommended name：Dual specificity tyrosine-phosphorylation-regulated kinase 2
EC number：EC:2.7.12.1
Alternative names：
Cleaved into：
GeneID：8445
Gene names (primary )：DYRK2
Gene names (synonym )：
Gene names (ORF )：
Length：601
Mass：66652
Sequence：MLTRKPSAAAPAAYPTGRGGDSAVRQLQASPGLGAGATRSGVGTGPPSPIALPPLRASNAAAAAHTIGGSKHTMNDHLHVGSHAHGQIQVQQLFEDNSNKRTVLTTQPNGLTTVGKTGLPVVPERQLDSIHRRQGSSTSLKSMEGMGKVKATPMTPEQAMKQYMQKLTAFEHHEIFSYPEIYFLGLNAKKRQGMTGGPNNGGYDDDQGSYVQVPHDHVAYRYEVLKVIGKGSFGQVVKAYDHKVHQHVALKMVRNEKRFHRQAAEEIRILEHLRKQDKDNTMNVIHMLENFTFRNHICMTFELLSMNLYELIKKNKFQGFSLPLVRKFAHSILQCLDALHKNRIIHCDLKPENILLKQQGRSGIKVIDFGSSCYEHQRVYTYIQSRFYRAPEVILGARYGMPIDMWSLGCILAELLTGYPLLPGEDEGDQLACMIELLGMPSQKLLDASKRAKNFVSSKGYPRYCTVTTLSDGSVVLNGGRSRRGKLRGPPESREWGNALKGCDDPLFLDFLKQCLEWDPAVRMTPGQALRHPWLRRRLPKPPTGEKTSVKRITESTGAITSISKLPPPSSSASKLRTNLAQMTDANGNIQQRTVLPKLVS
Tissue specificity：Testis, after the onset of spermatogenesis. {ECO:0000269|PubMed:9748265}.
Induction：Accumulates in nucleus upon DNA damage. Induced in both esophageal and lung adenocarcinomas. {ECO:0000269|PubMed:12874018, ECO:0000269|PubMed:19965871}.
Developmental stage：
Protein families：Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily