ABCE1_HUMAN P61221
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UniProt:P61221
Recommended name:ATP-binding cassette sub-family E member 1
EC number:EC:3.6.5.-
Alternative names:(2'-5'-oligoadenylate-binding protein) (HuHP68) (RNase L inhibitor) (Ribonuclease 4 inhibitor) (RNS4I)
Cleaved into:
GeneID:6059
Gene names (primary ):ABCE1
Gene names (synonym ):RLI RNASEL1 RNASELI RNS4I
Gene names (ORF ):OK/SW-cl.40
Length:599
Mass:67314
Sequence:MADKLTRIAIVNHDKCKPKKCRQECKKSCPVVRMGKLCIEVTPQSKIAWISETLCIGCGICIKKCPFGALSIVNLPSNLEKETTHRYCANAFKLHRLPIPRPGEVLGLVGTNGIGKSTALKILAGKQKPNLGKYDDPPDWQEILTYFRGSELQNYFTKILEDDLKAIIKPQYVDQIPKAAKGTVGSILDRKDETKTQAIVCQQLDLTHLKERNVEDLSGGELQRFACAVVCIQKADIFMFDEPSSYLDVKQRLKAAITIRSLINPDRYIIVVEHDLSVLDYLSDFICCLYGVPSAYGVVTMPFSVREGINIFLDGYVPTENLRFRDASLVFKVAETANEEEVKKMCMYKYPGMKKKMGEFELAIVAGEFTDSEIMVMLGENGTGKTTFIRMLAGRLKPDEGGEVPVLNVSYKPQKISPKSTGSVRQLLHEKIRDAYTHPQFVTDVMKPLQIENIIDQEVQTLSGGELQRVALALCLGKPADVYLIDEPSAYLDSEQRLMAARVVKRFILHAKKTAFVVEHDFIMATYLADRVIVFDGVPSKNTVANSPQTLLAGMNKFLSQLEITFRRDPNNYRPRINKLNSIKDVEQKKSGNYFFLDD
Tissue specificity:
Induction:Activated by encephalomyocarditis virus (EMCV) and HIV-1. {ECO:0000269|PubMed:9660177, ECO:0000269|PubMed:9847332}.
Developmental stage:
Protein families:ABC transporter superfamily, ABCE family