SOCS1_HUMAN O15524
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UniProt:O15524
Recommended name:Suppressor of cytokine signaling 1
EC number:
Alternative names:(SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Cleaved into:
GeneID:8651
Gene names (primary ):SOCS1
Gene names (synonym ):SSI1 TIP3
Gene names (ORF ):
Length:211
Mass:23551
Sequence:MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI
Tissue specificity:Expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes.
Induction:By a subset of cytokines including those belonging to the interferon, interleukin and colony-stimulating factor families.
Developmental stage:
Protein families:SOCS1 family