SOCS1_HUMAN   O15524


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UniProt:O15524

Recommended name:Suppressor of cytokine signaling 1

EC number:

Alternative names:(SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)

Cleaved into:

GeneID:8651

Gene names  (primary ):SOCS1

Gene names  (synonym ):SSI1 TIP3

Gene names  (ORF ):

Length:211

Mass:23551

Sequence:MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI

Tissue specificity:Expressed in all tissues with high expression in spleen, small intestine and peripheral blood leukocytes.

Induction:By a subset of cytokines including those belonging to the interferon, interleukin and colony-stimulating factor families.

Developmental stage:

Protein families:SOCS1 family


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