UBE2K_HUMAN P61086
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UniProt:P61086
Recommended name：Ubiquitin-conjugating enzyme E2 K
EC number：EC:2.3.2.23
Alternative names：(E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Cleaved into：
GeneID：3093
Gene names (primary )：UBE2K
Gene names (synonym )：HIP2 LIG
Gene names (ORF )：
Length：200
Mass：22407
Sequence：MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDAVVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN
Tissue specificity：Expressed in all tissues tested, including spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocytes, T-lymphocytes, monocytes, granulocytes and bone marrow mononuclear cells. Highly expressed in brain, with highest levels found in cortex and striatum and at lower levels in cerebellum and brainstem. {ECO:0000269|PubMed:10634809, ECO:0000269|PubMed:10675012, ECO:0000269|PubMed:8702625}.
Induction：By aggregated low-density lipoprotein. {ECO:0000269|PubMed:10634809, ECO:0000269|PubMed:10675012}.
Developmental stage：
Protein families：Ubiquitin-conjugating enzyme family