GPC5B_HUMAN Q9NZH0
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UniProt:Q9NZH0
Recommended name：G-protein coupled receptor family C group 5 member B
EC number：
Alternative names：(A-69G12.1) (Retinoic acid-induced gene 2 protein) (RAIG-2)
Cleaved into：
GeneID：51704
Gene names (primary )：GPRC5B
Gene names (synonym )：RAIG2
Gene names (ORF )：
Length：403
Mass：44795
Sequence：MFVASERKMRAHQVLTFLLLFVITSVASENASTSRGCGLDLLPQYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVRLPFIKEKEKKSPVGLHFLFLLGTLGLFGLTFAFIIQEDETICSVRRFLWGVLFALCFSCLLSQAWRVRRLVRHGTGPAGWQLVGLALCLMLVQVIIAVEWLVLTVLRDTRPACAYEPMDFVMALIYDMVLLVVTLGLALFTLCGKFKRWKLNGAFLLITAFLSVLIWVAWMTMYLFGNVKLQQGDAWNDPTLAITLAASGWVFVIFHAIPEIHCTLLPALQENTPNYFDTSQPRMRETAFEEDVQLPRAYMENKAFSMDEHNAALRTAGFPNGSLGKRPSGSLGKRPSAPFRSNVYQPTEMAVVLNGGTIPTAPPSHTGRHLW
Tissue specificity：Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}.
Induction：By all-trans retinoic acid (ATRA). {ECO:0000269|PubMed:10945465}.
Developmental stage：
Protein families：G-protein coupled receptor 3 family