PAWR_HUMAN Q96IZ0
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UniProt:Q96IZ0
Recommended name:PRKC apoptosis WT1 regulator protein
EC number:
Alternative names:(Prostate apoptosis response 4 protein) (Par-4)
Cleaved into:
GeneID:5074
Gene names (primary ):PAWR
Gene names (synonym ):PAR4
Gene names (ORF ):
Length:340
Mass:36568
Sequence:MATGGYRTSSGLGGSTTDFLEEWKAKREKMRAKQNPPGPAPPGGGSSDAAGKPPAGALGTPAAAAANELNNNLPGGAPAAPAVPGPGGVNCAVGSAMLTRAAPGPRRSEDEPPAASASAAPPPQRDEEEPDGVPEKGKSSGPSARKGKGQIEKRKLREKRRSTGVVNIPAAECLDEYEDDEAGQKERKREDAITQQNTIQNEAVNLLDPGSSYLLQEPPRTVSGRYKSTTSVSEEDVSSRYSRTDRSGFPRYNRDANVSGTLVSSSTLEKKIEDLEKEVVRERQENLRLVRLMQDKEEMIGKLKEEIDLLNRDLDDIEDENEQLKQENKTLLKVVGQLTR
Tissue specificity:Widely expressed. Expression is elevated in various neurodegenerative diseases such as amyotrophic lateral sclerosis, Alzheimer, Parkinson and Huntington diseases and stroke. Down-regulated in several cancers. {ECO:0000269|PubMed:8943350}.
Induction:By apoptosis.
Developmental stage:
Protein families: