GPR84_HUMAN Q9NQS5
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UniProt:Q9NQS5
Recommended name:G-protein coupled receptor 84
EC number:
Alternative names:(Inflammation-related G-protein coupled receptor EX33)
Cleaved into:
GeneID:53831
Gene names (primary ):GPR84
Gene names (synonym ):EX33
Gene names (ORF ):
Length:396
Mass:43705
Sequence:MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
Tissue specificity:Expressed predominantly in hematopoietic tissues. High levels detected in the bone marrow and lower levels in the peripheral leukocytes and lung. Also expressed in brain, heart, muscle, colon, thymus, spleen, kidney, liver, placenta and intestine. Within the leukocyte population expression is higher in neutrophils and eosinophils relative to T- or B-lymphocytes. {ECO:0000269|PubMed:11273702, ECO:0000269|PubMed:11404393, ECO:0000269|PubMed:16966319}.
Induction:By bacterial lipopolysaccharides (LPS) in the monocytic leukemia cell line THP-1. {ECO:0000269|PubMed:16966319}.
Developmental stage:
Protein families:G-protein coupled receptor 1 family