PLPL3_HUMAN Q9NST1
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UniProt:Q9NST1
Recommended name:1-acylglycerol-3-phosphate O-acyltransferase PNPLA3
EC number:EC:2.3.1.51
Alternative names:(Acylglycerol transacylase) (Adiponutrin) (ADPN) (Calcium-independent phospholipase A2-epsilon) (iPLA2-epsilon) (Lysophosphatidic acid acyltransferase) (Patatin-like phospholipase domain-containing protein 3)
Cleaved into:
GeneID:80339
Gene names (primary ):PNPLA3
Gene names (synonym ):ADPN C22orf20
Gene names (ORF ):
Length:481
Mass:52865
Sequence:MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLCKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFIPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPKGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL
Tissue specificity:
Induction:By changes in energy balance: down-regulated following very low-calorie diet, whereas refeeding elevates the mRNA level. {ECO:0000269|PubMed:15181042}.
Developmental stage:
Protein families: