ALKB5_HUMAN Q6P6C2
We list detailed information on various proteins on this webpage, which EnkiLife references when developing protein-related products. The protein data is sourced from UniProt, and since UniProt updates its information periodically, the data on our webpage may not always be up-to-date or may contain inaccuracies. If you notice any errors while browsing, we warmly welcome your feedback. Additionally, if you have any suggestions regarding any aspect of our website, please feel free to share them with us. As a token of our appreciation, we will offer a free product or a discount voucher for purchases to scientists who provide feedback. Please contact us at Email: order@enkilife.com; to share your feedback and get your rewards.
UniProt:Q6P6C2
Recommended name：RNA demethylase ALKBH5
EC number：EC:1.14.11.53
Alternative names：(Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)
Cleaved into：
GeneID：54890
Gene names (primary )：ALKBH5
Gene names (synonym )：ABH5 OFOXD1
Gene names (ORF )：
Length：394
Mass：44256
Sequence：MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPVSGAKRKYQEDSDPERSDYEEQQLQKEEEARKVKSGIRQMRLFSQDECAKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPEWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSVLPPSYASDRLSGNNRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCSEAAGSPARKVKMRRH
Tissue specificity：Widely expressed, with highest expression in lung, followed by testis, pancreas, spleen and ovary. {ECO:0000269|PubMed:17979886}.
Induction：By hypoxia, directly activated by HIF1A. Expression is regulated by PRMT7. {ECO:0000269|PubMed:21264265, ECO:0000269|PubMed:22761421}.
Developmental stage：
Protein families：AlkB family