PLAT3_HUMAN   P53816


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UniProt:P53816

Recommended name:Phospholipase A and acyltransferase 3

EC number:EC:2.3.1.-

Alternative names:(Adipose-specific phospholipase A2) (AdPLA) (Group XVI phospholipase A1/A2) (H-rev 107 protein homolog) (H-REV107) (HREV107-1) (HRAS-like suppressor 1) (HRAS-like suppressor 3) (HRSL3) (HREV107-3) (Renal carcinoma antigen NY-REN-65)

Cleaved into:

GeneID:11145

Gene names  (primary ):PLAAT3

Gene names  (synonym ):HRASLS3 HREV107 PLA2G16

Gene names  (ORF ):

Length:162

Mass:17937

Sequence:MRAPIPEPKPGDLIEIFRPFYRHWAIYVGDGYVVHLAPPSEVAGAGAASVMSALTDKAIVKKELLYDVAGSDKYQVNNKHDDKYSPLPCSKIIQRAEELVGQEVLYKLTSENCEHFVNELRYGVARSDQVRDVIIAASVAGMGLAAMSLIGVMFSRNKRQKQ

Tissue specificity:Widely expressed. low expression, if any, in hematopoietic cells and thymus. In testis, confined to round spermatids. Expressed in normal ovarian epithelial cells. Down-regulated in some ovarian carcinomas and testicular germ cell tumors. Highly expressed in white adipose tissue (PubMed:19136964). {ECO:0000269|PubMed:11526504, ECO:0000269|PubMed:11973642, ECO:0000269|PubMed:19136964, ECO:0000269|PubMed:19615464, ECO:0000269|PubMed:9771974}.

Induction:By IFNG and IRF1. {ECO:0000269|PubMed:11973642}.

Developmental stage:

Protein families:H-rev107 family


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