CXL11_HUMAN   O14625


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UniProt:O14625

Recommended name:C-X-C motif chemokine 11

EC number:

Alternative names:(Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)

Cleaved into:

GeneID:6373

Gene names  (primary ):CXCL11

Gene names  (synonym ):ITAC SCYB11 SCYB9B

Gene names  (ORF ):

Length:94

Mass:10365

Sequence:MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF

Tissue specificity:High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.

Induction:By IFNG/IFN-gamma and IFNB1/IFN-beta. Induction by IFNG/IFN-gamma is enhanced by TNF in monocytes, dermal fibroblasts and endothelial cells, and by IL1/interleukin-1 in astrocytes.

Developmental stage:

Protein families:Intercrine alpha (chemokine CxC) family


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