IL36A_HUMAN Q9UHA7
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UniProt:Q9UHA7
Recommended name:Interleukin-36 alpha
EC number:
Alternative names:(FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6)
Cleaved into:
GeneID:27179
Gene names (primary ):IL36A
Gene names (synonym ):FIL1E IL1E IL1F6
Gene names (ORF ):
Length:158
Mass:17684
Sequence:MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
Tissue specificity:Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin. {ECO:0000269|PubMed:11466363}.
Induction:By Il-1 and TNF-alpha. {ECO:0000269|PubMed:11466363}.
Developmental stage:
Protein families:IL-1 family