IL36A_HUMAN   Q9UHA7


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UniProt:Q9UHA7

Recommended name:Interleukin-36 alpha

EC number:

Alternative names:(FIL1 epsilon) (Interleukin-1 epsilon) (IL-1 epsilon) (Interleukin-1 family member 6) (IL-1F6)

Cleaved into:

GeneID:27179

Gene names  (primary ):IL36A

Gene names  (synonym ):FIL1E IL1E IL1F6

Gene names  (ORF ):

Length:158

Mass:17684

Sequence:MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF

Tissue specificity:Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin. {ECO:0000269|PubMed:11466363}.

Induction:By Il-1 and TNF-alpha. {ECO:0000269|PubMed:11466363}.

Developmental stage:

Protein families:IL-1 family


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