TNIP3_HUMAN Q96KP6
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UniProt:Q96KP6
Recommended name:TNFAIP3-interacting protein 3
EC number:
Alternative names:(A20-binding inhibitor of NF-kappa-B activation 3) (ABIN-3) (Listeria-induced gene protein)
Cleaved into:
GeneID:79931
Gene names (primary ):TNIP3
Gene names (synonym ):ABIN3 LIND
Gene names (ORF ):
Length:325
Mass:38943
Sequence:MAHFVQGTSRMIAAESSTEHKECAEPSTRKNLMNSLEQKIRCLEKQRKELLEVNQQWDQQFRSMKELYERKVAELKTKLDAAERFLSTREKDPHQRQRKDDRQREDDRQRDLTRDRLQREEKEKERLNEELHELKEENKLLKGKNTLANKEKEHYECEIKRLNKALQDALNIKCSFSEDCLRKSRVEFCHEEMRTEMEVLKQQVQIYEEDFKKERSDRERLNQEKEELQQINETSQSQLNRLNSQIKACQMEKEKLEKQLKQMYCPPCNCGLVFHLQDPWVPTGPGAVQKQREHPPDYQWYALDQLPPDVQHKANGLSSVKKVHP
Tissue specificity:Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}.
Induction:By Listeria infection. Expression is slightly down-regulated by dexamethasone and slightly up-regulated by IL-10. Strongly induced mRNA and protein expression by lipopolysaccharide. {ECO:0000269|PubMed:11345586, ECO:0000269|PubMed:17088249}.
Developmental stage:
Protein families: