DRAM1_HUMAN   Q8N682


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UniProt:Q8N682

Recommended name:DNA damage-regulated autophagy modulator protein 1

EC number:

Alternative names:(Damage-regulated autophagy modulator)

Cleaved into:

GeneID:55332

Gene names  (primary ):DRAM1

Gene names  (synonym ):DRAM

Gene names  (ORF ):

Length:238

Mass:26253

Sequence:MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI

Tissue specificity:

Induction:By p53/TP53 and p73/TP73. Directly activated by p53/TP53. Significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing. {ECO:0000269|PubMed:16839881, ECO:0000269|PubMed:17304243}.

Developmental stage:

Protein families:DRAM/TMEM150 family


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