DRAM1_HUMAN Q8N682
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UniProt:Q8N682
Recommended name:DNA damage-regulated autophagy modulator protein 1
EC number:
Alternative names:(Damage-regulated autophagy modulator)
Cleaved into:
GeneID:55332
Gene names (primary ):DRAM1
Gene names (synonym ):DRAM
Gene names (ORF ):
Length:238
Mass:26253
Sequence:MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI
Tissue specificity:
Induction:By p53/TP53 and p73/TP73. Directly activated by p53/TP53. Significantly down-regulated in tumor cell lines by methylation-dependent transcriptional silencing. {ECO:0000269|PubMed:16839881, ECO:0000269|PubMed:17304243}.
Developmental stage:
Protein families:DRAM/TMEM150 family