SHOX_HUMAN O15266
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UniProt:O15266
Recommended name:Short stature homeobox protein
EC number:
Alternative names:(Pseudoautosomal homeobox-containing osteogenic protein) (Short stature homeobox-containing protein)
Cleaved into:
GeneID:6473
Gene names (primary ):SHOX
Gene names (synonym ):PHOG
Gene names (ORF ):
Length:292
Mass:32236
Sequence:MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL
Tissue specificity:SHOXA is expressed in skeletal muscle, placenta, pancreas, heart and bone marrow fibroblast and SHOXB is highly expressed in bone marrow fibroblast followed by kidney and skeletal muscle. SHOXB is not expressed in brain, kidney, liver and lung. Highly expressed in osteogenic cells.
Induction:By retinoic acid and phorbol-12-myristate 13-acetate (PMA).
Developmental stage:
Protein families:Paired homeobox family, Bicoid subfamily