DHRS3_HUMAN O75911
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UniProt:O75911
Recommended name：Short-chain dehydrogenase/reductase 3
EC number：EC:1.1.1.300
Alternative names：(DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1)
Cleaved into：
GeneID：9249
Gene names (primary )：DHRS3
Gene names (synonym )：RDH17 SDR16C1
Gene names (ORF )：UNQ2424/PRO4983
Length：302
Mass：33548
Sequence：MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKGRT
Tissue specificity：Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retina, expressed in cone but not rod outer segments. {ECO:0000269|PubMed:11861404, ECO:0000269|PubMed:9705317}.
Induction：By retinoic acid. {ECO:0000269|PubMed:11861404}.
Developmental stage：
Protein families：Short-chain dehydrogenases/reductases (SDR) family