OLIG2_HUMAN   Q13516


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UniProt:Q13516

Recommended name:Oligodendrocyte transcription factor 2

EC number:

Alternative names:(Oligo2) (Class B basic helix-loop-helix protein 1) (bHLHb1) (Class E basic helix-loop-helix protein 19) (bHLHe19) (Protein kinase C-binding protein 2) (Protein kinase C-binding protein RACK17)

Cleaved into:

GeneID:10215

Gene names  (primary ):OLIG2

Gene names  (synonym ):BHLHB1 BHLHE19 PRKCBP2 RACK17

Gene names  (ORF ):

Length:323

Mass:32385

Sequence:MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK

Tissue specificity:Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. {ECO:0000269|PubMed:11498220, ECO:0000269|PubMed:11526205}.

Induction:By SHH. Also induced by NKX6-1 in the developing spinal cord, but not in the rostral hindbrain (By similarity). {ECO:0000250}.

Developmental stage:

Protein families:


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